Invention Grant
- Patent Title: Gene editing systems comprising an RNA guide targeting lactate dehydrogenase a (LDHA) and uses thereof
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Application No.: US18052791Application Date: 2022-11-04
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Publication No.: US11939607B2Publication Date: 2024-03-26
- Inventor: Quinton Norman Wessells , Jeffrey Raymond Haswell , Tia Marie Ditommaso , Noah Michael Jakimo , Sejuti Sengupta
- Applicant: Arbor Biotechnologies, Inc.
- Applicant Address: US MA Cambridge
- Assignee: ARBOR BIOTECHNOLOGIES, INC.
- Current Assignee: ARBOR BIOTECHNOLOGIES, INC.
- Current Assignee Address: US MA Cambridge
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Main IPC: C12N9/22
- IPC: C12N9/22 ; A61K31/7105 ; A61K38/46 ; A61K47/54 ; A61P13/12 ; C12N9/04 ; C12N15/10 ; C12N15/11 ; C12N15/86 ; C12N15/90
Abstract:
Provided herein are gene editing systems and/or compositions comprising RNA guides targeting LDHA for use in genetic editing of the LDHA gene. Also provide herein are methods of using the gene editing system for introducing edits to the LDHA gene and/or for treatment of primary hyperoxaluria (PH), and processes for characterizing the gene editing system.
Public/Granted literature
- US20230212540A1 GENE EDITING SYSTEMS COMPRISING AN RNA GUIDE TARGETING LACTATE DEHYDROGENASE A (LDHA) AND USES THEREOF Public/Granted day:2023-07-06
Information query
