A computer system causes output of audio information from a first application to a set of one or more audio output devices in accordance with a first audio output mode previously selected for the first application using a system audio output setting control. After, the computer system receives a request to play audio from a second application different from the first application. In response, the computer system causes output of audio information from the second application to the set of one or more audio output devices, including, in accordance with a determination that a second audio output mode, different from the first audio output mode, was previously selected for the second application using the system audio output setting control, causing output of the audio information from the second application via the set of one or more audio output devices in accordance with the second audio output mode.