Robotic Angioplasty and Endoluminar Surgery System to separate patient and operator by remotely moving guides and catheters during operations, composed of three or more elements, of which at least one disposable (nose), available in different versions, like for independent advancements and retractions of a balloon catheter (or stent) and relative guide and to their common axial rotation, or for moving a guide with a moving core or a catheter. The nose should be inserted into a non-sterile Slave placed near the patient, covered with sterile drapes, and with a combination of toothed wheels it translates all into three rotations controlled by three independent motors, possibly measuring the torque applied by the motors. By replacing the three angular gauges to the motors, a Master is obtained, controlled by a doctor by moving non-sterile tubes.