Invention Grant
- Patent Title: Combination therapy for treatment of LKB1 deficient cancers
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Application No.: US17466776Application Date: 2021-09-03
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Publication No.: US11944615B2Publication Date: 2024-04-02
- Inventor: David Peng , Kwok-Kin Wong , Jiehui Deng
- Applicant: New York University
- Applicant Address: US NY New York
- Assignee: New York University
- Current Assignee: New York University
- Current Assignee Address: US NY New York
- Agency: Hodgson Russ LLP
- Main IPC: A61K31/4545
- IPC: A61K31/4545 ; A61K31/497 ; A61K31/505 ; A61K45/06 ; A61P35/00
Abstract:
Provided are methods of sensitizing LKB1/STK11 deficient cancers to immune therapy. A method for treatment for LKB1/STK11 deficient cancers is provided comprising administration of inhibitor or inhibitors of one or more of NAMPT, CD38, SHP2, CXCR1/2, HDAC4 and PARP in combination with immunotherapy.
Public/Granted literature
- US20220062260A1 COMBINATION THERAPY FOR TREATMENT OF LKB1 DEFICIENT CANCERS Public/Granted day:2022-03-03
Information query
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