Invention Grant
- Patent Title: Stapled intracellular-targeting antimicrobial peptides to treat infection
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Application No.: US16813528Application Date: 2020-03-09
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Publication No.: US11945846B2Publication Date: 2024-04-02
- Inventor: Loren D. Walensky , Rida Mourtada
- Applicant: Dana-Farber Cancer Institute, Inc.
- Applicant Address: US MA Boston
- Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee Address: US MA Boston
- Agency: Fish & Richardson P.C.
- Main IPC: A61K38/08
- IPC: A61K38/08 ; A61K38/10 ; A61K38/17 ; A61K45/06 ; C07K7/06 ; C07K7/08 ; C07K14/435 ; C07K14/46 ; C07K14/47
Abstract:
Structurally stabilized, e.g., stapled, peptides with the ability to translocate through microbial cell membranes to the interior of microbial cells and exert a biological activity there are provided, as are methods of designing, making and using such peptides.
Public/Granted literature
- US20200308236A1 STAPLED INTRACELLULAR-TARGETING ANTIMICROBIAL PEPTIDES TO TREAT INFECTION Public/Granted day:2020-10-01
Information query
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