Invention Grant
- Patent Title: T-cell receptor constant region 1 antibody or T-cell receptor constant region 2 antibody
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Application No.: US17287307Application Date: 2019-12-21
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Publication No.: US11945867B2Publication Date: 2024-04-02
- Inventor: Martin Pulé , Shimobi Onuoha , Ana Margarida Neves , Mathieu Ferrari , Paul Maciocia
- Applicant: AUTOLUS LIMITED
- Applicant Address: GB London
- Assignee: AUTOLUS LIMITED
- Current Assignee: AUTOLUS LIMITED
- Current Assignee Address: GB London
- Agency: MARSHALL, GERSTEIN & BORUN LLP
- Priority: GB 17172 2018.10.22
- International Application: PCT/GB2019/053000 2019.12.21
- International Announcement: WO2020/084290A 2020.04.30
- Date entered country: 2021-04-21
- Main IPC: C07K16/28
- IPC: C07K16/28 ; G01N33/574
Abstract:
The present invention provides antibodies and polyclonal antibody preparations which bind the intracellular portion of either T-cell receptor constant region 2 (TRBC2) or T-cell receptor constant region 1 (TRBC1). The antibodies can be used to determine whether a T-cell malignancy clonally expresses TRBC1 or TRBC2.
Public/Granted literature
- US20210355217A1 T-CELL RECEPTOR CONSTANT REGION 1 ANTIBODY OR T-CELL RECEPTOR CONSTANT REGION 2 ANTIBODY Public/Granted day:2021-11-18
Information query
