Invention Grant
- Patent Title: Modification of D- and T-arms of tRNA enhancing D-amino acid and β-amino acid uptake
-
Application No.: US16755942Application Date: 2018-08-28
-
Publication No.: US11946042B2Publication Date: 2024-04-02
- Inventor: Hiroaki Suga , Takayuki Katoh
- Applicant: The University of Tokyo
- Applicant Address: JP Tokyo
- Assignee: The University of Tokyo
- Current Assignee: The University of Tokyo
- Current Assignee Address: JP Tokyo
- Agency: Canady + Lortz LLP
- Agent Suzannah K. Sundby, Esq.
- Priority: JP 17200356 2017.10.16
- International Application: PCT/JP2018/031814 2018.08.28
- International Announcement: WO2019/077887A 2019.04.25
- Date entered country: 2020-06-22
- Main IPC: C12N15/10
- IPC: C12N15/10 ; C12N15/113 ; C40B40/10
Abstract:
The purpose of the present invention is to provide, for translation in a cell-free translation system, a novel translation system capable of synthesizing a peptide having therein consecutive non-proteinogenic amino acids. The present invention provides a tRNA containing the base sequence represented by SEQ ID NO: 1 and encoding a non-proteinogenic amino acid.
Public/Granted literature
- US20200308572A1 Modification of D and T Arms of tRNA Enhancing D-Amino Acid and Beta-Amino Acid Uptake Public/Granted day:2020-10-01
Information query
IPC分类:
