Invention Grant
- Patent Title: Fusion protein comprising a Pab1 element and an eIF4G element and use of the fusion protein for improving protein synthesis
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Application No.: US16633524Application Date: 2017-12-13
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Publication No.: US11946084B2Publication Date: 2024-04-02
- Inventor: Min Guo , Shuailong Liu , Xue Yu
- Applicant: KangMa-Healthcode (Shanghai) Biotech Co., Ltd
- Applicant Address: CN Shanghai
- Assignee: KANGMA-HEALTHCODE (SHANGHAI) BIOTECH CO., LTD
- Current Assignee: KANGMA-HEALTHCODE (SHANGHAI) BIOTECH CO., LTD
- Current Assignee Address: CN Shanghai
- Agency: Wood, Phillips, Katz, Clark & Mortimer
- Priority: CN 1710642517.4 2017.07.31
- International Application: PCT/CN2017/115972 2017.12.13
- International Announcement: WO2019/024379A 2019.02.07
- Date entered country: 2020-05-22
- Main IPC: C12P21/00
- IPC: C12P21/00 ; C07K7/06 ; C12N15/86

Abstract:
Provided are a fusion protein comprising a Pab1 element and an eIF4G element and a preparation method therefor. The fusion protein can improve in-vitro translation efficiency. A constitutive or inducible promoter (for example, pKlPGK1) may also be inserted in front of eIF4G in the fusion protein for increasing in-vitro protein synthesis ability.
Public/Granted literature
- US20210189449A1 PREPARATION METHOD FOR NOVEL FUSION PROTEIN AND USE OF FUSION PROTEIN FOR IMPROVING PROTEIN SYNTHESIS Public/Granted day:2021-06-24
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