Invention Grant
- Patent Title: Methods for increasing mannose content of recombinant proteins
-
Application No.: US18134291Application Date: 2023-04-13
-
Publication No.: US11946085B2Publication Date: 2024-04-02
- Inventor: Chung-Jr Huang , Xiaoming Yang
- Applicant: Amgen Inc.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- The original application number of the division: US14289943 2014.05.29
- Main IPC: C12P21/00
- IPC: C12P21/00 ; C07K16/00 ; C12N5/00
Abstract:
The present invention relates to methods of upregulating the high mannose glycoform content of a recombinant protein during a mammalian cell culture by manipulating the mannose to total hexose ratio in the cell culture media formulation.
Public/Granted literature
- US20230250460A1 METHODS FOR INCREASING MANNOSE CONTENT OF RECOMBINANT PROTEINS Public/Granted day:2023-08-10
Information query
