The present disclosure is directed toward systems, methods, and non-transitory computer readable media for generating and suggesting content collections for user accounts of a content management system using combinations of content-based features such as textual signals and visual signals. In some embodiments, the disclosed systems select a seed content item from among a plurality of content items associated with a user account within a content management system. From the seed content item, the disclosed systems can determine one or more germane topics and can cluster additional content items in relation to the germane topic(s). In addition, the disclosed systems can select one or more content items from a content cluster to provide as a suggested content collection.