Invention Grant
- Patent Title: Chimeric antigen receptor that binds HLA-DR and CAR-T cell
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Application No.: US17188011Application Date: 2021-03-01
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Publication No.: US11951130B2Publication Date: 2024-04-09
- Inventor: Byoung S. Kwon , Young Ho Kim , Kwang Hee Kim , Ji Won Chung , Young Gyoon Chang , Bo Rim Yi , Jung Yun Lee , Seung Hyun Lee , Sun Woo Im , Jin Kyung Choi , Hyun Tae Son , Eun Hye Yoo
- Applicant: Eutilex Co., Ltd.
- Applicant Address: KR Seoul
- Assignee: Eutilex Co., Ltd.
- Current Assignee: Eutilex Co., Ltd.
- Current Assignee Address: KR Seoul
- Agent Vincent K. Shier
- The original application number of the division: US16715462 2019.12.16
- Main IPC: A61K35/17
- IPC: A61K35/17 ; A61P35/00 ; C07K16/28 ; C12N15/63

Abstract:
The present invention relates to an antigen-binding molecule comprising a heavy chain variable region comprising a heavy-chain complementarity-determining region 1 (HCDR1) comprising an amino acid sequence represented by Sequence No. 1, an HCDR2 comprising an amino acid sequence represented by Sequence No. 2, and an HCDR3 comprising an amino acid sequence represented by Sequence No. 3; a light-chain variable region comprising a light-chain complementarity-determining region 1 (LCDR1) comprising an amino acid sequence represented by Sequence No. 4, an LCDR2 comprising an amino acid sequence represented by Sequence No. 5, and an LCDR3 comprising an amino acid sequence represented by Sequence No. 6; wherein the antigen-binding molecule is a T cell receptor (TCR); and to a cell line expressing the same.
Public/Granted literature
- US20220031742A1 CHIMERIC ANTIGEN RECEPTOR THAT BINDS HLA-DR AND CAR-T CELL Public/Granted day:2022-02-03
Information query
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