Invention Grant
- Patent Title: Therapeutic molecules that bind to LAG3 and PD1
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Application No.: US16969905Application Date: 2019-02-18
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Publication No.: US11951172B2Publication Date: 2024-04-09
- Inventor: Carolyn Edwards , Angelica Sette , Isabelle Osuch , Yumin Teng , James Legg , David Escors Murugarren
- Applicant: CRESCENDO BIOLOGICS LIMITED
- Applicant Address: GB Cambridge
- Assignee: CRESCENDO BIOLOGICS LIMITED
- Current Assignee: CRESCENDO BIOLOGICS LIMITED
- Current Assignee Address: GB Cambridge
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Priority: GB 02573 2018.02.16
- International Application: PCT/GB2019/050425 2019.02.18
- International Announcement: WO2019/158942A 2019.08.22
- Date entered country: 2020-08-13
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K47/68 ; C07K16/18 ; C07K16/28 ; C12N15/10 ; C07K16/46

Abstract:
The invention relates to LAG-3 binding agents, in particular variable heavy chain (VH) sdAbs and bispecific agents that target both LAG-3 and PD-1, and the use of such binding agents in the treatment, prevention and detection of disease.
Public/Granted literature
- US20210015937A1 THERAPEUTIC MOLECULES THAT BIND TO LAG3 AND PD1 Public/Granted day:2021-01-21
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