Invention Grant
- Patent Title: Liquid hemostatic medical material
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Application No.: US17407982Application Date: 2021-08-20
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Publication No.: US11951229B2Publication Date: 2024-04-09
- Inventor: Hirotsugu Kido , Katsunori Chiba , Hironori Arima , Kenji Ohata
- Applicant: AOBAKASEI KABUSHIKI KAISHA , OSAKA CITY UNIVERSITY IN UNIVERSITY PUBLIC CORPORATION OSAKA
- Applicant Address: JP Sendai
- Assignee: AOBAKASEI KABUSHIKI KAISHA,OSAKA CITY UNIVERSITY IN UNIVERSITY PUBLIC CORPORATION OSAKA
- Current Assignee: AOBAKASEI KABUSHIKI KAISHA,OSAKA CITY UNIVERSITY IN UNIVERSITY PUBLIC CORPORATION OSAKA
- Current Assignee Address: JP Miyagi; JP Miyagi
- Agency: Oliff PLC
- Priority: JP 20139696 2020.08.20 JP 21104461 2021.06.23
- Main IPC: A61L26/00
- IPC: A61L26/00

Abstract:
To provide a liquid medical material maintaining a colloid in a more sol form than a solid at normal temperature, having a higher function as a wound dressing material and a hemostatic material than fibrin glue, and being able to be produced safely and inexpensively. A gelatin aqueous solution including calcium at a concentration of 0.2 M or more and 1.0 M or less, and having a concentration of 5% by weight or more and 40% by weight or less, an average molecular weight of 80,000 or more and 120,000 or less, and a molecular weight distribution of 20,000 or more and 300,000 or less, and transglutaminase inducing crosslinking of the gelatin, are included. It is preferable that the calcium has a concentration of 0.2 M or more and 0.7 M or less, the gelatin has a bloom of 160 or more and 250 or less, and the transglutaminase has activity per unit of 36 U/ml to 400 U/ml.
Public/Granted literature
- US20220054701A1 LIQUID MEDICAL MATERIAL Public/Granted day:2022-02-24
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