The present disclosure relates to the field of a pill dispenser. The pill dispenser with a pre-filled stackable cartridge comprises a top plate, fitted horizontally with an embedded machine device; a cartridge assembly, fitted horizontally and mounted vertically on top of each of the cartridge assembly, detachably supporting a set of the pre-filled stackable cartridge wherein each of the cartridge comprise a plurality of slots to place a pill and a pill dispensing slot for dispensing the pill; and a plurality of tabs attached externally to each of the cartridge wherein one of the tab remains intact and rest each of the tabs are broken to create at least one hole to denote a serial number of the cartridge to follow a sequence of mounting the cartridge, a base plate comprising a pill cup to be manually pulled by the consumer to extract the pill to be consumed.