Invention Grant
- Patent Title: Methods and systems for detection of antibiotic resistance
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Application No.: US16026462Application Date: 2018-07-03
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Publication No.: US11952611B2Publication Date: 2024-04-09
- Inventor: Minh Mindy Bao Nguyen , Dwight L. Anderson , Jose S. Gil , Stephen E. Erickson , Matthew J. Brown
- Applicant: Laboratory Corporation of America Holdings
- Applicant Address: US NC Burlington
- Assignee: Laboratory Corporation of America Holdings
- Current Assignee: Laboratory Corporation of America Holdings
- Current Assignee Address: US NC Burlington
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: C12Q1/14
- IPC: C12Q1/14 ; C12Q1/06 ; C12Q1/10 ; C12Q1/18 ; C12Q1/66 ; G01N33/569 ; C12N15/73 ; C12Q1/689
Abstract:
Disclosed herein are methods and systems for rapid detection of antibiotic resistance of a microorganism in a sample. A modified recombinant phage is also disclosed which comprises an indicator gene in the late gene region. The specificity of infectious agents allows a specific microorganism to be targeted, and an indicator signal may be amplified to optimize assay sensitivity.
Public/Granted literature
- US20190010534A1 Methods and Systems for Detection of Antibiotic Resistance Public/Granted day:2019-01-10
Information query
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