Invention Grant
- Patent Title: Digital sequence analysis of DNA methylation
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Application No.: US17101904Application Date: 2020-11-23
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Publication No.: US11952633B2Publication Date: 2024-04-09
- Inventor: David A. Ahlquist , William R. Taylor , Hongzhi Zou , Graham P. Lidgard
- Applicant: Exact Sciences Corporation , Mayo Foundation for Medical Education and Research
- Applicant Address: US WI Madison
- Assignee: Exact Sciences Corporation,Mayo Foundation for Medical Research and Education
- Current Assignee: Exact Sciences Corporation,Mayo Foundation for Medical Research and Education
- Current Assignee Address: US WI Madison; US MN Rochester
- Agency: Casimir Jones, S.C.
- Agent Mary Ann D. Brow
- The original application number of the division: US13364978 2012.02.02
- Main IPC: C12Q1/6886
- IPC: C12Q1/6886 ; C12Q1/6827 ; C12Q1/6858
Abstract:
The present invention relates to methods and compositions for determination of and uses of specific methylation patterns indicative of adenoma and carcinoma. In particular, the invention relates to analysis of defined CpG loci that are coordinately methylated in DNAs from cancer and adenoma samples, methods for identifying coordinately methylated loci, and methods of using analysis of coordinately methylated loci in one or more marker regions in the design of assays for adenoma and cancer.
Public/Granted literature
- US20210095350A1 DIGITAL SEQUENCE ANALYSIS OF DNA METHYLATION Public/Granted day:2021-04-01
Information query
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