Invention Grant
- Patent Title: Quantitation of insulin-like growth factor-I and insulin-like growth factor-II with high-resolution mass spectrometry
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Application No.: US17949863Application Date: 2022-09-21
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Publication No.: US11953507B2Publication Date: 2024-04-09
- Inventor: Cory Bystrom , Shijun Sheng , Nigel Clarke , Richard Reitz
- Applicant: Quest Diagnostics Investments Incorporated
- Applicant Address: US DE Wilmington
- Assignee: Quest Diagnostics Investments Incorporated
- Current Assignee: Quest Diagnostics Investments Incorporated
- Current Assignee Address: US DE Wilmington
- Agency: Foley & Lardner LLP
- Main IPC: G01N33/74
- IPC: G01N33/74 ; G01N33/68
Abstract:
Methods are provided for determining the amount of an IGF-I and/or IGF-II protein in a sample using high resolution/high accuracy mass spectrometry. The methods generally comprise enriching an IGF-I and/or IGF-II protein in a sample, ionizing an IGF-I and/or IGF-II protein from the sample to generate IGF-I and/or IGF-II protein ions, and determining the amount of IGF-I and/or IGF-II protein ions with high resolution/high accuracy mass spectrometry.
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