- Patent Title: Pharmaceutical compositions of tofacitinib for oral administration
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Application No.: US18447620Application Date: 2023-08-10
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Publication No.: US11957685B2Publication Date: 2024-04-16
- Inventor: Sushant Omprakash Dube , Purushottam Dattatraya Kulkarni , Purushottam Sakhahari Pattewar , Sumitra Ashokkumar Pillai
- Applicant: SLAYBACK PHARMA LLC
- Applicant Address: US NJ Princeton
- Assignee: SLAYBACK PHARMA LLC
- Current Assignee: SLAYBACK PHARMA LLC
- Current Assignee Address: US NJ Princeton
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: IN 2041017604 2020.04.24
- Main IPC: A61K31/277
- IPC: A61K31/277 ; A61K9/00 ; A61K9/08 ; A61K31/519 ; A61K47/12 ; A61K47/14 ; A61K47/20 ; A61K47/26 ; A61K47/40

Abstract:
Liquid pharmaceutical compositions of tofacitinib or its pharmaceutically acceptable salts thereof are described, which are suitable for oral administration, and which are stable under varying storage conditions for extended periods of time. Methods of treating auto-immune disorders are also described, using the stable liquid pharmaceutical compositions of tofacitinib. A stable liquid pharmaceutical composition of tofacitinib according to the invention comprises of (a) tofacitinib at a concentration of about 1 mg/mL or more; (b) a pharmaceutically acceptable liquid vehicle; (c) at least one anti-oxidant; and (d) optionally one or more other pharmaceutically acceptable excipients.
Public/Granted literature
- US20230398120A1 PHARMACEUTICAL COMPOSITIONS OF TOFACITINIB FOR ORAL ADMINISTRATION Public/Granted day:2023-12-14
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