Invention Grant
- Patent Title: Compositions and methods for treating cancer using RHOA dominant negative forms
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Application No.: US16761540Application Date: 2018-11-05
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Publication No.: US11957739B2Publication Date: 2024-04-16
- Inventor: Adam Bass , Haisheng Zhang
- Applicant: Dana-Farber Cancer Institute, Inc.
- Applicant Address: US MA Boston
- Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee Address: US MA Boston
- Agency: Foley Hoag LLP
- International Application: PCT/US2018/059188 2018.11.05
- International Announcement: WO2019/094326A 2019.05.16
- Date entered country: 2020-05-05
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/46 ; A61K39/00 ; G01N33/574 ; A61K45/06 ; A61K48/00

Abstract:
The present invention provides compositions and methods for treating cancers with reduced or absent CDH1 using a RHOA dominant negative polypeptide or biologically active fragment thereof, and/or a nucleic acid encoding a RHOA dominant negative polypeptide or biologically active fragment thereof.
Public/Granted literature
- US20200261550A1 COMPOSITIONS AND METHODS FOR TREATING CANCER USING RHOA DOMINANT NEGATIVE FORMS Public/Granted day:2020-08-20
Information query
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