The present invention provides a modular vise system comprised of a fixed body, a moveable body, and a fixture plate, wherein the moveable body has a wide range of motion which enables it to grab a piece of any size that will fit within the confines of the fixture plate, the moveable body being tightened from the top of the modular vise. Tightening of the modular vise from the top allows for multiple work pieces to be placed along the moving axis of the modular vise which increases workpiece density and machine efficiency. The moveable body of the modular vise may be driven mechanically, electrically, or via a fluid driven actuator such as a pneumatic actuator or a hydraulic actuator.