Invention Grant
- Patent Title: System and method using clinical data to predict genetic relatedness for the efficient management and reduction of healthcare-associated infections
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Application No.: US16455985Application Date: 2019-06-28
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Publication No.: US11961594B2Publication Date: 2024-04-16
- Inventor: Liyi Xu , Raivo Kolde , Andrew G. Hoss
- Applicant: KONINKLIJKE PHILIPS N.V.
- Applicant Address: NL Eindhoven
- Assignee: KONINKLIJKE PHILIPS N.V.
- Current Assignee: KONINKLIJKE PHILIPS N.V.
- Current Assignee Address: NL Eindhoven
- Main IPC: G16B5/20
- IPC: G16B5/20 ; G06N5/02 ; G16B20/20 ; G16B30/10 ; G16B40/20 ; G16B45/00 ; G16H40/20 ; G16H50/30 ; G16H50/50 ; G16H50/70 ; G16H50/80 ; G16H70/60 ; G16B20/40

Abstract:
A method for identifying two or more infections as related or non-related infections based on an estimated genetic relatedness of the two or more infections, comprising: (i) receiving, for each of two or more infected patients, infection-relevant information comprising an antibiotic resistance profile for the patient's infection, a geo-temporal record for the patient, and a caregiver history for the patient; (ii) estimating, using a trained genetic relatedness model, a genetic relatedness of at least two of the two or more infections; (iii) comparing the estimated genetic relatedness between at least two of the two or more infections to a predetermined threshold; (iv) identifying, based on the comparison, the at least two of the two or more infections as a related infection or a non-related infection.
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