A radio frequency (RF) unit and a method for RF isolation. The RF unit includes first and second RF couplers, an RF filter, and an RF canceler connected in parallel with the RF filter. The first RF coupler is configured to receive an input signal. The RF filter is configured to receive a first portion of the input signal from the first RF coupler and attenuate frequencies outside of a passband of the RF filter from the first portion of the input signal. The RF canceler is configured to receive a second portion of the input signal from the first RF coupler and generate a cancellation signal from the second portion of the input signal based on a target frequency band of the RF canceler. The second RF coupler is configured to combine the cancellation signal with an output of the RF filter to generate an output signal.