A system for detecting contamination in a two-phase immersion cooling system based on temperature differences between component surface temperature and fluid temperature, a previous component surface temperature and a present component surface temperature and a component surface temperature and a component surface temperature threshold value. Large differences between the component surface temperature and the fluid temperature or between the component surface temperature and a previous component surface temperature or a component surface temperature exceeding a component surface temperature threshold value may indicate contaminants in the fluid that are inhibiting the ability for the component to effectively transfer heat to the fluid. A temperature monitoring system may monitor the temperatures and communicate with a service system to apply corrective measures before the residue can cause significant damage to an information handling system.