Method and systems for creating clinical data files with secured medical information. A clinical data file may be created by converting clinical data to a single format, and the medical information may be entered into corresponding data fields in the clinical data file. The medical information may include treatment professional information, patient personal information, and/or patient image(s). Each of the data fields may be associated with an indicator, where the indicator, when enabled, may be configured to secure at least a portion of the medical information in the corresponding data field. The secured clinical data file may be configured such that, once a pass code is entered, the patient image(s) are modifiable by the addition of modification(s) that are arranged as layer(s) saved separately from the patient image(s).