Disclosed are a driving circuit, a driving method, and a display panel. The method includes: turning on the first thin film transistor to control the voltage of the first node to be an initialization voltage; then controlling the voltage of the second node to be a threshold voltage based on the respective voltage difference between the initialization voltage and the turned-on second and the fourth thin film transistor; turning on the third thin film transistor to compensate the threshold voltage to obtain a driving voltage; turning on the fifth thin film transistor to access the driving current by the driving voltage, the driving current is controlled to pass through the turned-on sixth thin film transistor to drive the light-emitting diode.