A system and a method for managing a clinical trial of patients. The method includes obtaining consents of the patients undergoing the clinical trial and storing consent data of the patients. Consent data of the patients is validated before progressing onto any stage of the clinical trial. Data associated with at least one clinical trial site is collected for performing the clinical trial. The patients are randomly grouped into two or more groups for performing one or more of a single blinded study and a double blinded study during the clinical trial. Clinical data and non-clinical data of the patients is collected during the clinical trial. Timelines, progress, compliance, and data associated with different stages of the clinical trial are managed.