Invention Grant
- Patent Title: Antibody/T-cell receptor chimeric constructs and uses thereof
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Application No.: US17181913Application Date: 2021-02-22
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Publication No.: US11976105B2Publication Date: 2024-05-07
- Inventor: Jingwei Lu , Zhiyuan Yang , Cheng Liu , Hong Liu , Yiyang Xu , Su Yan , Vivien Wai-Fan Chan , Lucas Horan
- Applicant: EUREKA THERAPEUTICS, INC.
- Applicant Address: US CA Emeryville
- Assignee: EUREKA THERAPEUTICS, INC.
- Current Assignee: EUREKA THERAPEUTICS, INC.
- Current Assignee Address: US CA Emeryville
- Agency: MORRISON & FOERSTER LLP
- Main IPC: C07K14/725
- IPC: C07K14/725 ; A61K35/17 ; A61K38/00 ; A61K39/00 ; A61K39/395 ; A61P35/00 ; C07K16/28 ; C12N15/62
Abstract:
The present application provides antibody-TCR chimeric constructs comprising an antibody moiety that specifically binds to a target antigen fused to a TCRM capable of recruiting at least one TCR-associated signaling module. Also provided are methods of making and using these constructs.
Public/Granted literature
- US20210253665A1 ANTIBODY/T-CELL RECEPTOR CHIMERIC CONSTRUCTS AND USES THEREOF Public/Granted day:2021-08-19
Information query
