Invention Grant
- Patent Title: Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use
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Application No.: US17199258Application Date: 2021-03-11
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Publication No.: US11976120B2Publication Date: 2024-05-07
- Inventor: Jon Weidanz , Katherine Upchurch-Ange
- Applicant: Boehringer Ingelheim International Gmbh
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agency: Goodwin Procter LLP
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61P35/00
Abstract:
Provided herein are antibodies that selectively bind to complex comprising a non-classical HLA-I (e.g. HLA-E) and a neoantigen having variable heavy chain domains (VH), variable light chain domains (VL), and complementarity determining regions (CDRs) as disclosed herein, as well as methods and uses thereof.
Public/Granted literature
- US20220033504A1 ANTIBODIES TARGETING A COMPLEX COMPRISING NON-CLASSICAL HLA-I AND NEOANTIGEN AND THEIR METHODS OF USE Public/Granted day:2022-02-03
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