Invention Grant
- Patent Title: Means and methods for generating midbrain organoids
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Application No.: US15766779Application Date: 2016-10-10
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Publication No.: US11976296B2Publication Date: 2024-05-07
- Inventor: Silvia Bolognin , Anna Monzel , Jens Schwamborn
- Applicant: UNIVERSITÉ DU LUXEMBOURG
- Applicant Address: LU Esch-sur-Alzette
- Assignee: UNIVERSITÉ DU LUXEMBOURG
- Current Assignee: UNIVERSITÉ DU LUXEMBOURG
- Current Assignee Address: LU Esch-sur-Alzette
- Agency: DITTHAVONG, STEINER & MLOTKOWSKI
- Priority: LU 845 2015.10.08
- International Application: PCT/IB2016/056054 2016.10.10
- International Announcement: WO2017/060884A 2017.04.13
- Date entered country: 2018-04-06
- Main IPC: C12N5/0793
- IPC: C12N5/0793 ; C12N5/079 ; G01N33/50
Abstract:
The present invention provides means and methods for the generation of midbrain organoids which are useful for studying neurodevelopmental and neurodegenerative diseases. Neuroepithelial stem cells serve as a starting population for the generation of midbrain organoids by contacting them with differentiation medium under agitating conditions in three-dimensional cell culture comprising a matrix.
Public/Granted literature
- US20180298330A1 MEANS AND METHODS FOR GENERATING MIDBRAIN ORGANOIDS Public/Granted day:2018-10-18
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