Invention Grant
- Patent Title: Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells
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Application No.: US16579798Application Date: 2019-09-23
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Publication No.: US11977076B2Publication Date: 2024-05-07
- Inventor: Jerome S. Brody , Avrum Spira , Jeffrey S. Berman , Anthony W. O'Regan
- Applicant: Trustees of Boston University
- Applicant Address: US MA Boston
- Assignee: Trustees of Boston University
- Current Assignee: Trustees of Boston University
- Current Assignee Address: US MA Boston
- Agency: Morse, Barnes-Brown & Pendleton, P.C.
- Agent Lisa M. Warren, Esq.; Erin E. Bryan, Esq.
- Main IPC: C12Q1/6886
- IPC: C12Q1/6886 ; G01N33/574
Abstract:
The present invention provides methods for diagnosis and prognosis of lung cancer using expression analysis of one or more groups of genes, and a combination of expression analysis from a nasal epithelial cell sample. The methods of the invention provide far less invasive method with a superior detection accuracy for lung cancer when compared to any other currently available method for lung cancer diagnostic or prognosis. The invention also provides methods of diagnosis and prognosis of other lung diseases, such as lung cancer.
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