In one implementation, an asynchronous communications system for distributing communications among selected users whereby those users can generate and distribute new content based upon received communications may include a server for maintaining a plurality of asynchronous communicated content. The communicated content includes a video communication, a transcript synchronized to at least a part of an audio track of the video communication, a distribution list of recipients of the communicated content, and any annotations made to the communicated content. The system further includes an interactive graphical user interface operable on a device of a user. The device is in communication with the server to access communicated content received by the user. The graphical user interface includes a video region for playing a video communication of communicated content, a transcript region for displaying at least a part of the transcript synchronized to an audio track of the video communication, and an interactive menu having annotation options for the user to select that is responsive to the user (i) highlighting a text excerpt from the synchronized transcript, (ii) selecting at least one of the asynchronous annotation options, and (iii) generating an annotation to be associated with the highlighted text excerpt.