A computer-implemented method for identifying features of interest in a data image. The method includes identifying data variations in a data image or set of data images, each data image comprising rendered data, identifying one or more features of interest in the data image or set of data images based on the identified data variations, identifying a feature of interest genus corresponding to each identified feature of interest, reclassifying the rendered data based on each of the identified features of interest genuses so as to eliminate background data in the rendered data thereby producing an eliminated background dataset, and generating a feature of interest map for each identified feature of interest genus. A machine learning method, including a training phase, for automatically identifying features of interest in a data image is further provided.