The present application refers to a control method and control device of a drive circuit, and a drive circuit. The control method of the drive circuit includes: acquiring a bus address in a bus signal. The bus signal is a signal transmitted over an I2C bus, and the I2C bus is connected to a timing controller. The control method further includes: if the timing controller determining that the bus address matches an address of the timing controller, transmitting a frequency adjustment signal to a controllable power supply with an adjustable operating frequency and connected to the timing controller. The frequency adjustment signal is configured to indicate that an operating frequency of the controllable power supply is adjusted from a first operating frequency to a second operating frequency. The second operating frequency is higher than the first operating frequency.