Invention Grant
- Patent Title: Compositions and methods for subcutaneous administration of cancer immunotherapy
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Application No.: US17568251Application Date: 2022-01-04
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Publication No.: US11980652B2Publication Date: 2024-05-14
- Inventor: Heather C. Losey , Jared Lopes , Lei Sun , Raymond J. Winquist
- Applicant: Mural Oncology, Inc.
- Applicant Address: US MA Waltham
- Assignee: Mural Oncology, Inc.
- Current Assignee: Mural Oncology, Inc.
- Current Assignee Address: US MA Waltham
- Agency: Fish & Richardson P.C.
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K9/00 ; A61K38/16 ; A61K39/395 ; A61P35/00 ; C07K16/28
Abstract:
The invention provides compositions, methods and treatment regimens for treating cancer comprising periodic subcutaneous administration of the fusion protein of SEQ ID NO:1 to a cancer patient resulting in enhanced activation of CD8+ T-cells with minimal effects on regulatory T cell (Treg) expansion and providing enhanced anti-tumor efficacy while also mitigating T cell inactivation/exhaustion.
Public/Granted literature
- US20220241370A1 COMPOSITIONS AND METHODS FOR SUBCUTANEOUS ADMINISTRATION OF CANCER IMMUNOTHERAPY Public/Granted day:2022-08-04
Information query
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