A tool change system includes: a seating portion configured to have a tool seated thereon; a tool changer disposed on a manipulator to separate the tool from the seating portion; and a pressing portion disposed on an upper side of the seating portion to release the tool from the tool changer. The tool changer includes: a main body disposed on the manipulator; and a gripper connected to the main body and including a hook to be locked into a locking recess formed on the tool and a lever pressed by the pressing portion.