Invention Grant
- Patent Title: Growth hormone receptor antagonists and fusion proteins thereof
-
Application No.: US16954902Application Date: 2018-12-20
-
Publication No.: US11981719B2Publication Date: 2024-05-14
- Inventor: Soon Jae Park , Jaehyeong Ko , Sun-Ah You , Sang Hoon Yun
- Applicant: Alteogen, Inc.
- Applicant Address: KR Daejeon
- Assignee: Alteogen, Inc.
- Current Assignee: Alteogen, Inc.
- Current Assignee Address: KR Daejeon
- Agency: Cooley LLP
- Priority: KR 20170176493 2017.12.20 KR 20180147700 2018.11.26
- International Application: PCT/KR2018/016311 2018.12.20
- International Announcement: WO2019/125002A 2019.06.27
- Date entered country: 2020-06-17
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K47/62 ; C07K14/61 ; C07K14/81
Abstract:
The present invention relates to a growth hormone receptor antagonist comprising a growth hormone variant which is modified by substitution of one or more amino acids of growth hormone. Further, the growth hormone receptor antagonist of the present invention may further comprise a long-acting carrier which is fused to the growth hormone variant. The growth hormone receptor antagonist may have strong binding potency to growth hormone receptor and may exhibit a long-lasting antagonistic action.
Information query
IPC分类:
