Invention Grant
- Patent Title: Methods for treating conditions associated with MASP-2 dependent complement activation
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Application No.: US16984509Application Date: 2020-08-04
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Publication No.: US11981749B2Publication Date: 2024-05-14
- Inventor: Gregory A. Demopulos , Thomas A. Dudler , Hans-Wilhelm Schwaeble
- Applicant: Omeros Corporation , University of Leicester
- Applicant Address: US WA Seattle
- Assignee: OMEROS CORPORATION,UNIVERSITY OF LEICESTER
- Current Assignee: OMEROS CORPORATION,UNIVERSITY OF LEICESTER
- Current Assignee Address: US WA Seattle; GB Leicester
- Agent Tineka J. Quinton; Glenda A. Gertz
- Main IPC: A61P7/02
- IPC: A61P7/02 ; A61P37/02 ; C07K16/40 ; A61K39/00
Abstract:
In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a human subject suffering from TMA associated with hematopoietic stem cell transplant. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation.
Public/Granted literature
- US20210047433A1 Methods for Treating Conditions Associated with MASP-2 Dependent Complement Activation Public/Granted day:2021-02-18
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