Invention Grant
- Patent Title: Therapeutic hydrogels and contact lens for corneal melting
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Application No.: US17256354Application Date: 2019-06-28
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Publication No.: US11981760B2Publication Date: 2024-05-14
- Inventor: Jung-Jae Lee , Kyung Jae Jeong
- Applicant: THE REGENTS OF THE UNIVERSITY OF COLORADO , UNIVERSITY OF NEW HAMPSHIRE
- Applicant Address: US CO Denver
- Assignee: The Regents of the University of Colorado, a body corporate,University of New Hampshire
- Current Assignee: The Regents of the University of Colorado, a body corporate,University of New Hampshire
- Current Assignee Address: US CO Denver; US NH Durham
- Agency: Saul Ewing LLP
- Agent Domingos J. Silva; Alireza Behrooz
- International Application: PCT/US2019/039916 2019.06.28
- International Announcement: WO2020/006471A 2020.01.02
- Date entered country: 2020-12-28
- Main IPC: C08F20/40
- IPC: C08F20/40 ; A61K9/00 ; A61P27/02 ; C07D213/38 ; C08J3/075
Abstract:
The present invention relates to the unexpected discovery of a cross-linked polymer of 2-hydroxyethyl methacrylate and dipicolylamine-containing monomers that can be used as a therapeutic lens to treat ocular diseases or disorders associated with matrix metalloproteinase (MMP) over-activity and/or over-expression, such as but not limited to corneal melting (or keratolysis).
Public/Granted literature
- US20210261701A1 THERAPEUTIC HYDROGELS AND CONTACT LENS FOR CORNEAL MELTING Public/Granted day:2021-08-26
Information query
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