Invention Grant
- Patent Title: Methods and materials for the effective use of combined targeted enrichment of genomic regions and low coverage whole genome sequencing
-
Application No.: US16310171Application Date: 2017-06-16
-
Publication No.: US11981962B2Publication Date: 2024-05-14
- Inventor: Jean-Pierre A. Kocher , Chen Wang
- Applicant: Mayo Foundation for Medical Education and Research
- Applicant Address: US MN Rochester
- Assignee: Mayo Foundation for Medical Education and Research
- Current Assignee: Mayo Foundation for Medical Education and Research
- Current Assignee Address: US MN Rochester
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2017/037819 2017.06.16
- International Announcement: WO2017/218864A 2017.12.21
- Date entered country: 2018-12-14
- Main IPC: C12Q1/6869
- IPC: C12Q1/6869 ; C12Q1/6806 ; C12Q1/686 ; C12Q1/6876 ; C12Q1/6886 ; G16B20/00 ; G16B20/20 ; G16B25/00 ; G16B25/20 ; G16B30/00
Abstract:
This document provides methods and materials for using low coverage whole genome sequencing techniques to assess genomes. For example, methods and materials for using targeted nucleic acid amplification and/or capture techniques in combination with low coverage whole genome sequencing techniques to obtain high coverage sequencing data for one or more pre-selected regions of a genome are provided.
Public/Granted literature
Information query
