An image filling method and apparatus, a device and a storage medium are disclosed. The image filling method includes: performing multilevel encoding processing on features of an image to be filled to generate multilevel encoded feature layers, sizes of the multilevel encoded feature layers being reduced layer by layer; performing layer-by-layer decoding processing on the multilevel encoded feature layers to obtain multilevel decoded feature layers and a first image, there being no missing region in the first image, wherein the layer-by-layer decoding processing includes a concatenation operation on a decoded feature layer and an encoded feature layer with a same size; and performing up-sampling processing on the first image to obtain multilevel up-sampled feature layers and a second image optimized by the up-sampling processing, the up-sampling processing including a concatenation operation on an up-sampled feature layer and a decoded feature layer with a same size.