A system may include an ultrasound probe and a controller unit configured to communicate with the ultrasound probe. The controller unit may be further configured to select an aiming mode for an ultrasound probe; detect a target of interest; determine a centroid for the detected target of interest; display a center indicator based on the determined centroid; detect that the center indicator is within a threshold number of pixels or distance of a centerline of a field of view of the ultrasound probe; and highlight the generated center indicator, in response to detecting that the center indicator is within the threshold number of pixels or distance of the centerline.