Aspects of the present disclosure provide ultrasound systems and devices that provide for reduction of reverberation artifacts in ultrasound images by automatically changing imaging settings such as PRI or transmit/receive configuration based on detected amounts of reverberation in ultrasound images. In an exemplary embodiment, an apparatus includes a processor circuit in communication with an ultrasound probe. The processor circuit obtains a plurality of ultrasound images obtained using a plurality of different PRIs and/or pulse sequences, calculates an amount of reverberation artifacts in each of the plurality of ultrasound images, selects a pulse repetition interval and/or pulse sequence based on the amounts of reverberation artifacts in each of the plurality of ultrasound images, and controls the ultrasound transducer to obtain a reduced-reverberation ultrasound image using the selected pulse repetition interval or pulse sequence. The reduced-reverberation ultrasound image is then output to a display.