The use of plasma to clean or sterilize items can be particularly advantageous for items that cannot be readily washed or cleaned by standard methods. The toxicity and complications generating sufficient plasma makes it hard to use for such purposes. The subject invention addresses the problem by generating a minimal amount of highly reactive plasma to sterilize an item. This is achieved by reducing the amount of space and ambient air around and within the item. In this way, the plasma generated fills only the required volume of the item to be cleaned and the plasm is directed at the object, not directed at or released into non-target areas.