Invention Grant
- Patent Title: Microdevice for differential separation, purification and amplification of forensic samples
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Application No.: US16484142Application Date: 2018-02-07
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Publication No.: US11986822B2Publication Date: 2024-05-21
- Inventor: Tracey Dawson Green , James Landers
- Applicant: VIRGINIA COMMONWEALTH UNIVERSITY
- Applicant Address: US VA Richmond
- Assignee: Virginia Commonwealth University,University of Virginia Patent Foundation
- Current Assignee: Virginia Commonwealth University,University of Virginia Patent Foundation
- Current Assignee Address: US VA Richmond; US VA Charlottesville
- Agency: WC&F IP
- International Application: PCT/US2018/017213 2018.02.07
- International Announcement: WO2018/148271A 2018.08.16
- Date entered country: 2019-08-07
- Main IPC: B01L3/00
- IPC: B01L3/00 ; B01L7/00 ; C12Q1/686

Abstract:
Microfluidic devices for analyzing cellular components from biological samples which contain more than one cell type are provided. The microdevice separates cells by type, releases cellular components such as DNA (e.g. by cell lysis) and processes the cellular components (for example, by amplification) to generate products of interest for further analysis. Samples that can be analyzed using the microfluidic devices include forensic samples such as samples from sexual assault victims, and the products of interest include short tandem repeat (STR) amplicons for DNA profiling.
Public/Granted literature
- US20200023366A1 MICRODEVICE FOR DIFFERENTIAL SEPARATION, PURIFICATION AND AMPLIFICATION OF FORENSIC SAMPLES Public/Granted day:2020-01-23
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