A method of additively manufacturing a three-dimensional object may be performed using an irradiation sequence that is based at least in part on a predicted location of one or more fume plumes emitted from the powder material when irradiated by a plurality of energy beams. An exemplary method may include determining, with a computing device, an irradiation sequence for selectively consolidating powder material using an energy beam system of an additive manufacturing machine, and providing control commands, from the computing device to the energy beam system, configured to cause the energy beam system to emit a plurality of energy beams to selectively consolidate the powder material.