Invention Grant
- Patent Title: Solid support for synthesizing nucleic acid sequences and methods for making and using
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Application No.: US18003404Application Date: 2021-06-28
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Publication No.: US11987599B2Publication Date: 2024-05-21
- Inventor: Serge L. Beaucage , Andrzej M. Grajkowski
- Applicant: United States of America, as represented by the Secretary, Department of Health and Human Services
- Applicant Address: US MD Silver Spring
- Assignee: United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US MD Silver Spring
- Agency: Klarquist Sparkman, LLP
- International Application: PCT/US2021/039403 2021.06.28
- International Announcement: WO2022/005988A 2022.01.06
- Date entered country: 2022-12-27
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07F9/09 ; C07F9/655 ; C07H21/00 ; C07H21/02 ; C12N15/10 ; C12N15/113 ; C40B50/18

Abstract:
Disclosed herein are embodiments of a solid support suitable for synthesizing nucleic acid sequences. The solid support may have a structure according to Formula I, where CPG is controlled pore glass, and m, n, x, y, R1 and R2 are as defined herein.
Also disclosed are methods for making and using the solid support, kits including solid support, and a universal linker phosphoramidite suitable for use in the solid support.
Also disclosed are methods for making and using the solid support, kits including solid support, and a universal linker phosphoramidite suitable for use in the solid support.
Public/Granted literature
- US20230271998A1 SOLID SUPPORT FOR SYNTHESIZING NUCLEIC ACID SEQUENCES AND METHODS FOR MAKING AND USING Public/Granted day:2023-08-31
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