A bidirectional transient voltage suppressor (TVS) protection circuit includes two sets of steering diodes, a clamp circuit including an MOS transistor integrated with a silicon controlled rectifier (SCR) and a trigger circuit. In response to a voltage applied to one of the protected nodes exceeding a first voltage level, the trigger circuit drives the MOS transistor to cause a current flow at the SCR to trigger an SCR action and the SCR clamps the voltage at the respective protected node at a clamping voltage. In other embodiments, a bidirectional transient voltage suppressor (TVS) protection circuit includes two sets of steering diodes with a clamp device merged with a steering diode in each set. In some embodiments, the TVS protection circuit realizes low capacitance at the protected nodes by fully or almost completely depleting the P-N junction connected to the protected nodes in the operating voltage range.