Invention Grant
- Patent Title: Method and device for continuously synthesizing cyclopropane compounds
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Application No.: US17622294Application Date: 2019-07-02
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Publication No.: US11993552B2Publication Date: 2024-05-28
- Inventor: Hao Hong , Jiangping Lu , Xichun Feng , Xingfang Sun , Feng Zhang
- Applicant: ASYMCHEM LABORATORIES (TIANJIN) CO., LTD.
- Applicant Address: CN Tianjin
- Assignee: ASYMCHEM LABORATORIES (TIANJIN) CO., LTD.
- Current Assignee: ASYMCHEM LABORATORIES (TIANJIN) CO., LTD.
- Current Assignee Address: CN Tianjin
- Agency: Riverside Law LLP
- International Application: PCT/CN2019/094345 2019.07.02
- International Announcement: WO2021/000248A 2021.01.07
- Date entered country: 2021-12-23
- Main IPC: C07C2/86
- IPC: C07C2/86 ; C07B37/02

Abstract:
The present disclosure discloses a method and a device for continuously synthesizing cyclopropane compounds. The method includes the following steps: continuously performing a synthetic reaction of a diazomethane precursor in a first reactor, the reaction product of the first reactor flowing into a separator for stratification, the organic phase obtained by stratification overflowing into a second reactor, continuously consuming the diazomethane precursor in a second reactor to prepare diazomethane and performing an electron-rich monoolefin cyclopropanation reaction in situ so as to obtain the cyclopropane compound.
Public/Granted literature
- US20220242805A1 Method and Device for Continuously Synthesizing Cyclopropane Compounds Public/Granted day:2022-08-04
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