Invention Grant
- Patent Title: Methods to create chemically-induced dimerizing protein systems for regulation of cellular events
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Application No.: US17203473Application Date: 2021-03-16
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Publication No.: US11993794B2Publication Date: 2024-05-28
- Inventor: Rupesh Amin
- Applicant: Fred Hutchinson Cancer Center
- Applicant Address: US WA Seattle
- Assignee: FRED HUTCHINSON CANCER CENTER
- Current Assignee: FRED HUTCHINSON CANCER CENTER
- Current Assignee Address: US WA Seattle
- Agency: Lee & Hayes P.C.
- The original application number of the division: US15770433
- Main IPC: C12N9/52
- IPC: C12N9/52 ; C07K14/705 ; C07K16/00 ; C07K16/44 ; C07K16/46 ; C12N9/50 ; C12N9/64 ; C12N9/96 ; C12N15/70 ; C12N15/81
Abstract:
Methods to create chemically-induced dimerizing (CID) protein systems and uses thereof are described. The methods utilize antibody binding domain dimerizing proteins. The created systems can be used to regulate cellular events such as gene expression, receptor signaling and cell death to effectuate a variety of clinically relevant treatment outcomes.
Public/Granted literature
- US20210198646A1 METHODS TO CREATE CHEMICALLY-INDUCED DIMERIZING PROTEIN SYSTEMS FOR REGULATION OF CELLULAR EVENTS Public/Granted day:2021-07-01
Information query
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