Invention Grant
- Patent Title: Method for analyzing cell sample heterogeneity
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Application No.: US17260572Application Date: 2019-07-17
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Publication No.: US11993809B2Publication Date: 2024-05-28
- Inventor: Christin Sünkel , Nikolaos Karaiskos , Nikolaus Rajewsky
- Applicant: MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT
- Applicant Address: DE Berlin
- Assignee: MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT
- Current Assignee: MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT
- Current Assignee Address: DE Berlin
- Agency: SALIWANCHIK, LLOYD & EISENSCHENK
- Priority: EP 184151 2018.07.18
- International Application: PCT/EP2019/069295 2019.07.17
- International Announcement: WO2020/016327A 2020.01.23
- Date entered country: 2021-01-15
- Main IPC: C12Q1/6841
- IPC: C12Q1/6841 ; C12N15/10 ; C12Q1/6876
Abstract:
The present invention relates to a method for analyzing a biological sample on a single cell level by compartmentalizing said sample using a grid and performing an optimized combinatorial indexing protocol within cells of the compartmentalized tissue while deducing cell-specific information regarding the cell identity and activity in the spatial context within the sample.
Public/Granted literature
- US20220162685A1 METHOD FOR ANALYZING CELL SAMPLE HETEROGENEITY Public/Granted day:2022-05-26
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